Comparison

Anti-TSH-Receptor, B-Chain Antibody

Item no. ABC-AH13560-U0100
Manufacturer Abcepta
Amount 100 ug
Category
Type Antibody Primary
Applications FC, IF, IHC-P
Clone TSHRB/1405
Specific against other
Host Mouse
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products CHNG1; hTSHRI; LGR3; Thyroid-stimulating hormone receptor; Thyrotropin receptor; Thyrotropin receptor I; TSHR
Available
Primary Accession
P16473
Antigen Type
Recombinant protein
Application
IHC-P, IF, FC
Bio Background
Thyroid-stimulating hormone (TSH, also known as thyrotropin) is a glycoprotein involved in the control of thyroid structure and metabolism, which stimulates the release of the thyroid hormones. TSH is regulated by thyroid hormone (T3) and various retinoid compounds. TSH binds to the thyroid-stimulating hormone receptor (TSHR), which is cleaved into two subunits, A and B, and plays a major role in regulating thyroid function. The third cytoplasmic loop of TSHR has been identified as critical for its role in regulating inositol phosphate and cAMP formation. In Grave s disease, an autoimmune disorder, TSHR is activated by autoantibodies, which may be stimulated by the cleavage of the A and B subunits.
Clonality
Monoclonal
Gene ID
7253
Gene Name
TSHR
Subtitle
Mouse Monoclonal Antibody
Reactivity
H
Legend image 1
Formalin-fixed, paraffin-embedded human Thyroid Carcinoma stained with TSHRB Monoclonal Antibody (TSHRB/1405).
Type image 1
IHC-P
Other Accession
160411
Clone: TSHRB/1405

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100 ug
Available: In stock
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