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Junctophilin 2 / JPH2 Antibody (C-Terminus)

Junctophilin 2 / JPH2 Antibody (C-Terminus)

Item no.	ABC-ALS13023
Manufacturer	Abcepta
Amount	50 ug
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Applications	WB, ELISA, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	JPH2, JP2, Junctophilin-2, Junctophilin type 2, JP-2
Available
Primary Accession	Q9BR39
Antigen Type	Synthetic peptide
Application	WB, IHC-P, E
Bio Background	Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. JPH2 is necessary for proper intracellular Ca(2+) signaling in cardiac myocytes via its involvement in ryanodine receptor-mediated calcium ion release. Contributes to the construction of skeletal muscle triad junctions.
Bio References	Stavrides G.S., et al.Submitted (NOV-1999) to the EMBL/GenBank/DDBJ databases. Deloukas P., et al.Nature 414:865-871(2001). Mural R.J., et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. Nishi M., et al.Biochem. Biophys. Res. Commun. 273:920-927(2000). Olsen J.V., et al.Cell 127:635-648(2006).
Clonality	Polyclonal
Gene ID	57158
Gene Name	JPH2 (HGNC:14202)
Subtitle	Rabbit Polyclonal Antibody
Reactivity	H, M, Rat
Legend image 1	Anti-JPH2 antibody IHC of human heart.
Type image 1	IHC
Legend image 2	Anti-JPH2 antibody IHC of human skeletal muscle.
Type image 2	IHC
Calculated MW	74222
Target/Specificity	Multiple isoforms of JPH2 are known to exist.
Purification	Immunoaffinity purified
Concentration (mg/ml)	1 mg/ml
Reconstitution & Storage	Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
Dilution	IHC-P (5 µg/ml), WB (1-2 µg/ml),

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 50 ug

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