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BECN1 Antibody (Ascites)

BECN1 Antibody (Ascites)

Item no.	ABC-AM1818b
Manufacturer	Abcepta
Amount	100 ul
Category	Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Immunofluorescence Autophagy Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, IF, IHC-P
Clone	117CT2.5.1.1
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgM Kappa
Citations	Age at onset in Huntington's disease is modified by the autophagy pathway: implication of the V471A polymorphism in Atg7. Metzger S, et al. Hum Genet, 2010 Oct. PMID 20697744. Interaction of Beclin 1 with survivin regulates sensitivity of human glioma cells to TRAIL-induced apoptosis. Niu TK, et al. FEBS Lett, 2010 Aug 20. PMID 20638385. Regulation of amyloid precursor protein processing by the Beclin 1 complex. Jaeger PA, et al. PLoS One, 2010 Jun 15. PMID 20559548. Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors. Li Z, et al. BMC Cancer, 2010 Mar 16. PMID 20230646. Over-expression of the Beclin1 gene upregulates chemosensitivity to anti-cancer drugs by enhancing therapy-induced apoptosis in cervix squamous carcinoma CaSki cells. Sun Y, et al. Cancer Lett, 2010 Aug 28. PMID 20207475.
NCBI	NP_003757.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Beclin-1,Coiled-coil myosin-like BCL2-interacting protein,Protein GT197,BECN1,GT197
Similar products	Beclin-1, BECN1, GT197, Coiled-coil myosin-like BCL2-interacting protein, Protein GT197
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Metabolism; Microbiology; Antiviral defense; Host-virus interaction; Autophagy; Mitochondrion; Regulation of autophagy
Manufacturer - Targets	This BECN1 Monoclonal antibody was raised using purified His-tagged recombinant full length human Autophagy BECN1.
Bio Background	Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 29 [PubMed 1927693]).
Clonality	Monoclonal
Gene Name	BECN1
Subtitle	Mouse Monoclonal Antibody (Mab)
Reactivity	H
Calculated Molecular Weight	51896
Antigen Source	HUMAN
Formulation	Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Dilution	IF: 1:10~50 WB: 1:500~1000 IHC-P: 1:50~100
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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Delivery expected until 1/1/2026

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