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URM1 Antibody

URM1 Antibody

Item no.	ABC-AM1883a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Cell Biology Cell Status Western Blot Autophagy Primary Antibodies
Type	Antibody Monoclonal
Applications	Western Blot
Clone	RB49774
Specific against	other
Host	Mouse
Isotype	IgM kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Ubiquitin-related modifier 1 {ECO:0000255\|HAMAP-Rule:MF_03048}, URM1 {ECO:0000255\|HAMAP-Rule:MF_03048}, C9orf74
Available
Primary Accession	Q9BTM9
Antigen Type	Recombinant Protein
Bio Background	Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by thiocarboxylated (-COSH) at its C-terminus by MOCS3. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. May also act as an ubiquitin-like protein that is covalently conjugated to other proteins; the relevance of such function is however unclear in vivo.
Bio References	Schlieker, C.D., et al. Proc. Natl. Acad. Sci. U.S.A. 105(47):18255-18260(2008) Schmitz, J., et al. Biochemistry 47(24):6479-6489(2008) Xu, J., et al. Proc. Natl. Acad. Sci. U.S.A. 103(31):11625-11630(2006) Singh, S., et al. Protein Sci. 14(8):2095-2102(2005) Humphray, S.J., et al. Nature 429(6990):369-374(2004)
Gene ID	81605
Gene Name	URM1 {ECO:0000255\|HAMAP-Rule:MF_03048}
Reactivity	H
Calculated MW	11380
Antigen Source	HUMAN
Target/Specificity	This URM1 monoclonal antibody is generated from mouse immunized with URM1 recombinant protein.
NCBI Accession	NP_001129419.1; NP_112176.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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