RAB8A Antibody

Primary Antibodies; Signal Transduction; SARS CoV2 PPIs

The protein encoded by this gene is a member of the RASsuperfamily which are small GTP/GDP-binding proteins with anaverage size of 2 amino acids. The RAS-related proteins of theRAB/YPT family may play a role in the transport of proteins fromthe endoplasmic reticulum to the Golgi and the plasma membrane.This protein shares 97%, 96%, and 51% similarity with the dog RAB8, mouse MEL, and mouse YPT1 proteins, respectively and contains the 4GTP/GDP-binding sites that are present in all the RAS proteins. Theputative effector-binding site of this protein is similar to thatof the RAB/YPT proteins. However, this protein contains aC-terminal CAAX motif that is characteristic of many RASsuperfamily members but which is not found in YPT1 and the majorityof RAB proteins. Although this gene was isolated as a transforminggene from a melanoma cell line, no linkage between MEL andmalignant melanoma has been demonstrable. This oncogene is located8 kb distal to MY9B on chromosome 19p13.1.

RAB8A

H, M

23668

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Recombinant Protein