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BMI1 Antibody

BMI1 Antibody

Item no.	ABC-AM1930b-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Neuroscience Molecular Targets for Neuroscience Antibodies By Cell Type Carcinoma Hematology Leukemia Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, IF
Clone	282CT3.7.6
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1 Kappa
Citations	Ismail, I.H., et al. J. Cell Biol. 191(1):45-60(2010) Yang, M.H., et al. Nat. Cell Biol. 12(10):982-992(2010) Kikuchi, J., et al. Cancer 116(12):3015-3024(2010) Honig, A., et al. Anticancer Res. 30(5):1559-1564(2010) Venkataraman, S., et al. PLoS ONE 5 (6), E10748 (2010) :
NCBI	NP_001190991.1,NP_005171.4
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Polycomb complex protein BMI-1,Polycomb group RING finger protein 4,RING finger protein 51,BMI1,PCGF4,RNF51
Similar products	PCGF4, BMI1, RNF51, Polycomb complex protein BMI-1, Polycomb group RING finger protein 4, RING finger protein 51
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cell Biology; Signal Transduction; Ubiquitin E3 Ligases (RING Domain) Antibodies
Manufacturer - Targets	This BMI1 monoclonal antibody is generated from mouse immunized with BMI1 recombinant protein.
Bio Background	Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Clonality	Monoclonal
Gene Name	BMI1
Subtitle	Mouse Monoclonal Antibody (Mab)
Reactivity	H
Calculated Molecular Weight	36949
Antigen Source	HUMAN
Formulation	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Dilution	IF: 1:10~50 WB: 1:500~1000 WB: 1:1000
Antigen Type	Recombinant Protein

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 3/5/2026

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