CD4 Antibody

Primary Antibodies; Immunology; Signal Transduction; Host cell receptor for virus entry; Host-virus interaction; Immunity; Immune system process; T cell receptor signaling

This gene encodes a membrane glycoprotein of T lymphocytesthat interacts with major histocompatibility complex class IIantigenes and is also a receptor for the human immunodeficiencyvirus. This gene is expressed not only in T lymphocytes, but alsoin B cells, macrophages, and granulocytes. It is also expressed inspecific regions of the brain. The protein functions to initiate oraugment the early phase of T-cell activation, and may function asan important mediator of indirect neuronal damage in infectious andimmune-mediated diseases of the central nervous system. Multiplealternatively spliced transcript variants encoding differentisoforms have been identified in this gene.

CD4

H

HUMAN

WB: 1:500~1000