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CD68 Antibody(Ascites)

CD68 Antibody(Ascites)

Item no.	ABC-AM1996a
Manufacturer	Abcepta
Amount	100 ul
Category	Neuroscience Neural Lineage Markers Antibodies Western Blot Primary Antibodies Calcium Binding Protein Markers
Type	Antibody Monoclonal
Applications	WB
Clone	404CT9.2.5
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgG1
Citations	Leonarduzzi, G., et al. Mol Nutr Food Res 54 SUPPL 1, S31-S41 (2010): Strojnik, T., et al. Anticancer Res. 29(8):3269-3279(2009) Sayed, S., et al. Eur J Vasc Endovasc Surg 38(1):20-25(2009) Suzuki, Y., et al. Int J Rheum Dis 12(1):7-13(2009) Chen, W.S., et al. Scand. J. Rheumatol. 38(2):154-155(2009)
NCBI	NP_001035148.1,NP_001242.2
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Macrosialin,Gp110,CD68,CD68
Similar products	CD68, Macrosialin, Gp110
Available
Manufacturer - Category	Primary Antibodies; Immunology; Lysosome
Manufacturer - Targets	This CD68 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 133-160 amino acids from human CD68.
Bio Background	This gene encodes a 11-kD transmembrane glycoprotein thatis highly expressed by human monocytes and tissue macrophages. Itis a member of the lysosomal/endosomal-associated membraneglycoprotein (LAMP) family. The protein primarily localizes tolysosomes and endosomes with a smaller fraction circulating to thecell surface. It is a type I integral membrane protein with aheavily glycosylated extracellular domain and binds to tissue- andorgan-specific lectins or selectins. The protein is also a memberof the scavenger receptor family. Scavenger receptors typicallyfunction to clear cellular debris, promote phagocytosis, andmediate the recruitment and activation of macrophages. Alternativesplicing results in multiple transcripts encoding differentisoforms.
Clonality	Monoclonal
Gene Name	CD68
Subtitle	Mouse Monoclonal Antibody (Mab)
Reactivity	H
Calculated Molecular Weight	37408
Antigen Source	HUMAN
Antigen Region	133-160
Formulation	Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide.
Dilution	WB: 1:1000~4000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 100 ul

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