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GAD2 Antibody

GAD2 Antibody

Item no.	ABC-AM2049b-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Neuroscience Neuroinflammation Molecular Targets for Neuroscience Neural Signaling Antibodies Western Blot Primary Antibodies
Type	Antibody Monoclonal
Applications	WB
Clone	458CT17.2.4
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Mouse
Isotype	IgG1
Citations	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Jia, P., et al. Schizophr. Res. 122 (1-3), 38-42 (2010): Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010) Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010): Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
NCBI	NP_000809.1,NP_001127838.1
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Glutamate decarboxylase 2,65 kDa glutamic acid decarboxylase,GAD-65,Glutamate decarboxylase 65 kDa isoform,GAD2,GAD65
Similar products	GAD-65, GAD2, GAD65, Glutamate decarboxylase 2, 65 kDa glutamic acid decarboxylase, Glutamate decarboxylase 65 kDa isoform
Available
Manufacturer - Category	Primary Antibodies; Metabolism; Neuroscience
Manufacturer - Targets	This GAD2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 445-473 amino acids from human GAD2.
Bio Background	This gene encodes one of several forms of glutamic aciddecarboxylase, identified as a major autoantigen ininsulin-dependent diabetes. The enzyme encoded is responsible forcatalyzing the production of gamma-aminobutyric acid fromL-glutamic acid. A pathogenic role for this enzyme has beenidentified in the human pancreas since it has been identified as anautoantibody and an autoreactive T cell target in insulin-dependentdiabetes. This gene may also play a role in the stiff man syndrome.Alternative splicing results in multiple transcript variants thatencode the same protein.
Clonality	Monoclonal
Gene Name	GAD2
Subtitle	Mouse Monoclonal Antibody (Mab)
Reactivity	H, M, Rat
Calculated Molecular Weight	65411
Antigen Source	HUMAN
Antigen Region	445-473
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:500 WB: 1:500
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 3/5/2026

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