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CD33 Antibody

CD33 Antibody

Item no.	ABC-AM2149b
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Neuroscience Neuroinflammation Antibodies By Cell Type Hematology Leukemia Myeloma Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Monoclonal
Applications	WB, IF
Clone	574CT16.4.4
Specific against	Human (Homo sapiens)
Host	Mouse
Isotype	IgM
Citations	Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010): Davila, S., et al. Genes Immun. 11(3):232-238(2010) Akahane, K., et al. Leukemia 24(4):865-869(2010) Shamsasenjan, K., et al. Int. J. Hematol. 89(3):310-318(2009) Bertram, L., et al. Am. J. Hum. Genet. 83(5):623-632(2008)
NCBI	NP_001076087.1,NP_001171079.1,NP_001763.3
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Myeloid cell surface antigen CD33,Sialic acid-binding Ig-like lectin 3,Siglec-3,gp67,CD33,CD33,SIGLEC3
Similar products	CD33, SIGLEC3, Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, gp67, Siglec-3
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cardiovascular; Immunology; Signal Transduction
Manufacturer - Targets	This CD33 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 337-364 amino acids from human CD33.
Bio Background	Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2, 6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Clonality	Monoclonal
Gene Name	CD33
Subtitle	Mouse Monoclonal Antibody (Mab)
Reactivity	H
Calculated Molecular Weight	39825
Antigen Source	HUMAN
Antigen Region	337-364
Formulation	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.
Dilution	IF: 1:10~50 WB: 1:500~1000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 3/5/2026

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