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TSG101 Antibody

TSG101 Antibody

Item no.	ABC-AM8662b-ev-50ul
Manufacturer	Abcepta
Amount	50 ul
Category	Antibodies Western Blot Primary Antibodies
Type	Antibody Monoclonal
Applications	Western Blot
Specific against	other
Host	Mouse
Isotype	IgG1 kappa
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	Tumor susceptibility gene 101 protein, ESCRT-I complex subunit TSG101, TSG101
Available
Primary Accession	Q99816
Antigen Type	Synthesized Peptide
Bio Background	Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.
Bio References	Li L., et al.Cell 88:143-154(1997). Li L., et al.Cell 93:661-661(1998). Gayther S.A., et al.Oncogene 15:2119-2126(1997). Lee M.P., et al.Cancer Res. 57:3131-3134(1997). Wagner K.-U., et al.Oncogene 17:2761-2770(1998).
Gene ID	7251
Gene Name	TSG101
Reactivity	H
Calculated MW	43944
Antigen Source	HUMAN
Target/Specificity	This antibody is generated from a mouse immunized with a recombinant protein from human.

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Amount: 50 ul

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