SERPINI1 Antibody (N-term)

Synthetic Peptide

This gene encodes a member of the serpin superfamily of
serine proteinase inhibitors. The protein is primarily secreted by
axons in the brain, and preferentially reacts with and inhibits
tissue-type plasminogen activator. It is thought to play a role in
the regulation of axonal growth and the development of synaptic
plasticity. Mutations in this gene result in familial
encephalopathy with neuroserpin inclusion bodies (FENIB), which is
a dominantly inherited form of familial encephalopathy and epilepsy
characterized by the accumulation of mutant neuroserpin polymers.
Multiple alternatively spliced variants, encoding the same protein,
have been identified.

Polyclonal

5274

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Confocal immunofluorescent analysis of SERPINI1 Antibody (N-term)(Cat#AP10388a) with HepG2 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

1:10~50

WB

SERPINI1 antibody (N-term) (Cat. #AP10388a) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SERPINI1 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

1:50~100

FC

NP_001116224.1

46427

HUMAN

NP_001116224.1; NP_005016.1