Comparison

FOLR1 Antibody (N-term)

Item no. ABC-AP10693a-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot, Flow cytometry
Clone RB52883
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Folate receptor alpha, FR-alpha, Adult folate-binding protein, FBP, Folate receptor 1, Folate receptor, adult, KB cells FBP, Ovarian tumor-associated antigen MOv18, FOLR1, FOLR
Available
Primary Accession
P15328
Other Accession
O15254; NP_000793.1
Antigen Type
Synthetic Peptide
Bio Background
The protein encoded by this gene is a member of the folate
receptor family. Members of this gene family bind folic acid and
its reduced derivatives, and transport 5-methyltetrahydrofolate
into cells. This gene product is a secreted protein that either
anchors to membranes via a glycosyl-phosphatidylinositol linkage or
exists in a soluble form. Mutations in this gene have been
associated with neurodegeneration due to cerebral folate transport
deficiency. Due to the presence of two promoters, multiple
transcription start sites, and alternative splicing, multiple
transcript variants encoding the same protein have been found for
this gene.
Bio References
Sivakumaran, S., et al. J. Steroid Biochem. Mol. Biol. 122(5):333-340(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
O'Byrne, M.R., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(8):689-694(2010)
Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :
Elwood, P.C., et al. Biochemistry 36(6):1467-1478(1997)
Gene ID
2348
Gene Name
FOLR1
Reactivity
H
Calculated MW
29819
Antigen Region
33-68
Antigen Source
HUMAN
Target/Specificity
This FOLR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-68 amino acids from the N-terminal region of human FOLR1.
NCBI Accession
NP_000793.1; NP_057936.1; NP_057937.1; NP_057941.1

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