BCL10 Antibody (N-term)

Primary Antibodies; Cancer; Cell Biology; Metabolism; Signal Transduction; Immunity; B cell receptor signaling; Immune system process; T cell receptor signaling

This gene was identified by its translocation in a case ofmucosa-associated lymphoid tissue (MALT) lymphoma. The proteinencoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB.This protein is reported to interact with other CARD domaincontaining proteins including CARD9, 1, 11 and 14, which arethought to function as upstream regulators in NF-kappaB signaling.This protein is found to form a complex with MALT1, a proteinencoded by another gene known to be translocated in MALT lymphoma.MALT1 and this protein are thought to synergize in the activationof NF-kappaB, and the deregulation of either of them may contributeto the same pathogenetic process that leads to the malignancy.

RB24271

Affinity Purified Rabbit Polyclonal Antibody (Pab)

Rat

HUMAN

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Synthetic Peptide

B-cell lymphoma/leukemia 10, B-cell CLL/lymphoma 10, Bcl-10, CARD-containing molecule enhancing NF-kappa-B, CARD-like apoptotic protein, hCLAP, CED-3/ICH-1 prodomain homologous E10-like regulator, CIPER, Cellular homolog of vCARMEN, cCARMEN, Cellular-E10, c-E10, Mammalian CARD-containing adapter molecule E10, mE10, BCL10, CIPER, CLAP