Item no. |
ABC-AP11162A-ev-80ul |
Manufacturer |
Abcepta
|
Amount |
80 ul |
Category |
|
Type |
Antibody Polyclonal |
Applications |
Immunofluorescence, Western Blot, Immunohistochemistry |
Clone |
RB53330 |
Specific against |
other |
Host |
Rabbit |
Isotype |
Ig |
ECLASS 10.1 |
32160702 |
ECLASS 11.0 |
32160702 |
UNSPSC |
12352203 |
Alias |
Integrator complex subunit 11, Int11, 3127-, Cleavage and polyadenylation-specific factor 3-like protein, CPSF3-like protein, Protein related to CPSF subunits of 68 kDa, RC-68, CPSF3L, INTS11, RC68 |
Available |
|
Primary Accession |
Q5TA45 |
Other Accession |
Q3MHC2; Q9CWS4; Q2YDM2; NP_060341.2 |
Antigen Type |
Synthetic Peptide |
Bio Background |
The Integrator complex contains at least 12 subunits and associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates the 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit of the Integrator complex (Baillat et al., 2005 [PubMed 16239144]). |
Bio References |
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Baillat, D., et al. Cell 123(2):265-276(2005) Dominski, Z., et al. Mol. Cell. Biol. 25(4):1489-1500(2005) |
Gene ID |
54973 |
Gene Name |
|
Reactivity |
H |
Predicted |
B, M, Rat |
Calculated MW |
67663 |
Antigen Region |
91-119 |
Antigen Source |
HUMAN |
Target/Specificity |
This CPSF3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the N-terminal region of human CPSF3L. |
NCBI Accession |
NP_001243385.1; NP_001243389.1; NP_001243391.1; NP_001243392.1; NP_060341.2 |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.