Comparison

PDE4B Antibody (Center)

Item no. ABC-AP11684c
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications WB, FC
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products PDE4B, DPDE4, cAMP-specific 3', 5'-cyclic phosphodiesterase 4B, PDE32
Available
Primary Accession
Q07343
Antigen Type
Synthetic Peptide
Application
WB, FC
Bio Background
This gene is a member of the type IV, cyclic AMP
(cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family.
Cyclic nucleotides are important second messengers that regulate
and mediate a number of cellular responses to extracellular
signals, such as hormones, light, and neurotransmitters. The cyclic
nucleotide phosphodiesterases (PDEs) regulate the cellular
concentrations of cyclic nucleotides and thereby play a role in
signal transduction. This gene encodes a protein that specifically
hydrolyzes cAMP. Altered activity of this protein has been
associated with schizophrenia and bipolar affective disorder.
Alternate transcriptional splice variants, encoding different
isoforms, have been characterized.
Bio References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Souza, R.P., et al. Int Clin Psychopharmacol 25(5):264-269(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Joslyn, G., et al. Alcohol. Clin. Exp. Res. 34(5):800-812(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Clonality
Polyclonal
Clone/Animal Names
RB18545
Gene ID
5142
Gene Name
PDE4B
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
PDE4B Antibody (Center) (Cat. #AP11684c) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the PDE4B antibody detected the PDE4B protein (arrow).
Type image 1
WB
Dilution image 1
1:1000
Legend image 2
PDE4B Antibody (Center) (Cat. #AP11684c) flow cytometric analysis of Ramos cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Type image 2
FC
Dilution image 2
1:10~50
Other Accession
NP_002591.2; NP_001032418.1
Isotype
Rabbit Ig
Calculated MW
83343
Antigen Region
189-217
Antigen Source
HUMAN
Target/Specificity
This PDE4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 189-217 amino acids from the Central region of human PDE4B.
NCBI Accession
NP_001032416.1; NP_001032417.1; NP_001032418.1; NP_002591.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
available

Delivery expected until 9/4/2025 

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