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Ubiquitin Antibody

Ubiquitin Antibody

Item no.	ABC-AP1229A-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Immunofluorescence Autophagy Primary Antibodies
Type	Antibody Polyclonal
Applications	Immunofluorescence, Western Blot, Immunohistochemistry
Clone	RB58813
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Polyubiquitin-C, Ubiquitin, UBC
Available
Primary Accession	P0CG48
Other Accession	P62975; P62972; P0CG69; P62976; P0CG71; P0CG63; Q63429; P0CG68; P0CG50; P0CH28; P0CG51; P0CG49; P0CG47; P0CG62; P0CG53; P05759; P62982; P62983; P62979; P15357; P79781; P62992; P62986; P63053; P62984; P0C273; P62987; P18101; P49632; P63048; P0CH09; P0CH08;
Antigen Type	Synthetic Peptide
Bio Background	This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin is required for ATP-dependent, nonlysosomal intracellular protein degradation of abnormal proteins and normal proteins with a rapid turnover. Ubiquitin is covalently bound to proteins to be degraded, and presumably labels these proteins for degradation. Ubiquitin also binds to histone H2A in actively transcribed regions but does not cause histone H2A degradation, suggesting that ubiquitin is also involved in regulation of gene expression. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. Aberrant form of this protein has been noticed in patients with Alzheimer's and Down syndrome.
Bio References	Chan, Y.L., et al., Biochem. Biophys. Res. Commun. 215(2):682-690 (1995). Cook, W.J., et al., J. Mol. Biol. 236(2):601-609 (1994). Hubbard, M.J., et al., Biochim. Biophys. Acta 1200(2):191-196 (1994). Wajih, N., et al., Protein Seq. Data Anal. 5(1):31-32 (1992). Cook, W.J., et al., J. Biol. Chem. 267(23):16467-16471 (1992).
Gene ID	7316
Gene Name	UBC
Reactivity	H
Predicted	Y, B, E, D, Pr, M, Pig, Rat, Sh, C, Hs, Ha, X, Rb
Calculated MW	77039
Antigen Region	36-66
Antigen Source	HUMAN
Target/Specificity	This Ubiquitin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-66 amino acids of human Ubiquitin.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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