« Back
Home /
PIAS3 Antibody (C-term)

PIAS3 Antibody (C-term)

Item no.	ABC-AP1244a-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Antibodies Carcinoma Obesity Immunohistochemistry Western Blot Enzymes Fatty Acid Synthesis Primary Antibodies
Type	Antibody Polyclonal
Applications	Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	E3 SUMO-protein ligase PIAS3, 632-, Protein inhibitor of activated STAT protein 3, PIAS3
Available
Primary Accession	Q9Y6X2
Other Accession	O70260; O54714
Antigen Type	Synthetic Peptide
Bio Background	PIAS3 is a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. The protein functions as a SUMO (small ubiquitin-like modifier)-E3 ligase stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor, catalyzing the covalent attachment of a SUMO protein to specific target substrates. PIAS3 plays a crucial role as a transcriptional coregulator in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.
Bio References	Nojiri, S., et al., Biochem. Biophys. Res. Commun. 314(1):97-103 (2004). Long, J., et al., Proc. Natl. Acad. Sci. U.S.A. 101(1):99-104 (2004). Cheng, J., et al., Leuk. Res. 28(1):71-82 (2004). Yamamoto, T., et al., Biochem. Biophys. Res. Commun. 306(2):610-615 (2003). Ueki, N., et al., J. Hum. Genet. 44(3):193-196 (1999).
Gene ID	10401
Gene Name	PIAS3
Reactivity	H
Predicted	M, Rat
Calculated MW	68017
Antigen Region	588-619
Antigen Source	HUMAN
Target/Specificity	This PIAS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-619 amino acids of human PIAS3.
NCBI Accession	NP_006090.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

ABC-AP1244a-ev-80ul-datasheet.pdf

Request safety datasheet

Simple Order Order Subscription

Amount: 80 ul

not available