Comparison

HIST1H2BL Antibody (N-term)

Item no. ABC-AP12710a-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot, Flow cytometry
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Histone H2B type 1-L, Histone H2Bc, H2B/c, HIST1H2BL, H2BFC
Available
Primary Accession
Q99880
Other Accession
Q64524; NP_003510.1
Antigen Type
Synthetic Peptide
Bio Background
Histones are basic nuclear proteins that are responsible
for the nucleosome structure of the chromosomal fiber in
eukaryotes. Two molecules of each of the four core histones (H2A,
H2B, H3, and H4) form an octamer, around which approximately 146 bp
of DNA is wrapped in repeating units, called nucleosomes. The
linker histone, H1, interacts with linker DNA between nucleosomes
and functions in the compaction of chromatin into higher order
structures. This gene is intronless and encodes a member of the
histone H2B family. Transcripts from this gene lack polyA tails but
instead contain a palindromic termination element. This gene is
found in the small histone gene cluster on chromosome 6p22-p21.3.
Bio References
Kim, S.C., et al. Mol. Cell 23(4):607-618(2006)
Beck, H.C., et al. Mol. Cell Proteomics 5(7):1314-1325(2006)
Pavri, R., et al. Cell 125(4):703-717(2006)
Bonenfant, D., et al. Mol. Cell Proteomics 5(3):541-552(2006)
Zhu, B., et al. Mol. Cell 20(4):601-611(2005)
Gene ID
8340
Gene Name
H2BC13 (HGNC:4748)
Reactivity
H
Predicted
M
Calculated MW
13952
Antigen Region
1-30
Antigen Source
HUMAN
Target/Specificity
This HIST1H2BL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2BL.
NCBI Accession
NP_003510.1

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