Comparison

SEC62 Antibody (N-term)

Item no. ABC-AP12850a-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot, Immunohistochemistry
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Translocation protein SEC62, Translocation protein 1, TP-1, hTP-1, SEC62, TLOC1
Available
Primary Accession
Q99442
Other Accession
Q8BU14; NP_003253.1
Antigen Type
Synthetic Peptide
Bio Background
The Sec61 complex is the central component of the protein
translocation apparatus of the endoplasmic reticulum (ER) membrane.
The protein encoded by this gene and SEC63 protein are found to be
associated with ribosome-free SEC61 complex. It is speculated that
Sec61-Sec62-Sec63 may perform post-translational protein
translocation into the ER. The Sec61-Sec62-Sec63 complex might also
perform the backward transport of ER proteins that are subject to
the ubiquitin-proteasome-dependent degradation pathway. The encoded
protein is an integral membrane protein located in the rough ER.
Bio References
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Lim, J., et al. Cell 125(4):801-814(2006)
Jung, V., et al. Mol. Cancer Res. 4(3):169-176(2006)
Meyer, H.A., et al. J. Biol. Chem. 275(19):14550-14557(2000)
Gene ID
7095
Gene Name
SEC62
Reactivity
H
Predicted
M
Calculated MW
45862
Antigen Region
1-30
Antigen Source
HUMAN
Target/Specificity
This SEC62 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SEC62.
NCBI Accession
NP_003253.1

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