Comparison

GCDH Antibody (C-term)

Item no. ABC-AP12905b-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot, Immunohistochemistry
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Glutaryl-CoA dehydrogenase, mitochondrial, GCD, GCDH
Available
Primary Accession
Q92947
Other Accession
Q8HXX8; Q2KHZ9; NP_000150.1; NP_039663.1
Antigen Type
Synthetic Peptide
Bio Background
The protein encoded by this gene belongs to the acyl-CoA
dehydrogenase family. It catalyzes the oxidative decarboxylation of
glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway
of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses
electron transfer flavoprotein as its electron acceptor. The enzyme
exists in the mitochondrial matrix as a homotetramer of 45-kD
subunits. Alternatively spliced transcript variants encoding
different isoforms have been identified.
Bio References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Park, J.D., et al. J. Korean Med. Sci. 25(6):957-960(2010)
Strauss, K.A., et al. Brain 133 (PT 1), 76-92 (2010) :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Ganesh, S.K., et al. Nat. Genet. 41(11):1191-1198(2009)
Gene ID
2639
Gene Name
GCDH
Reactivity
H
Predicted
B, Pr
Calculated MW
48127
Antigen Region
336-365
Antigen Source
HUMAN
Target/Specificity
This GCDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-365 amino acids from the C-terminal region of human GCDH.
NCBI Accession
NP_000150.1; NP_039663.1

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