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Bad Antibody (Center)

Bad Antibody (Center)

Item no.	ABC-AP1314C
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Cell Biology Cell Status Apoptosis Immunohistochemistry Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Lee, J.W., et al., Carcinogenesis 25(8):1371-1376 (2004). Zhang, B., et al., Mol. Cell. Biol. 24(14):6205-6214 (2004). Ong, C.S., et al., Oncol. Rep. 11(3):727-733 (2004). Yan, B., et al., J. Biol. Chem. 278(46):45358-45367 (2003). Taghiyev, A.F., et al., Mol. Cancer Res. 1(7):500-507 (2003).
NCBI	NP_004313.1,NP_116784.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Bcl2-associated agonist of cell death,BAD,Bcl-2-binding component 6,Bcl-2-like protein 8,Bcl2-L-8,Bcl-xL/Bcl-2-associated death promoter,Bcl2 antagonist of cell death,BAD,BBC6,BCL2L8
Similar products	BAD, Bcl2 antagonist of cell death, Bcl-2-binding component 6, Bcl-xL/Bcl-2-associated death promoter, BBC6, BCL2L8, Bcl-2-like protein 8, Bcl2-associated agonist of cell death, Bcl2-L-8
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Cell Biology; Metabolism; Signal Transduction; Amyotrophic Lateral Sclerosis (ALS); Apoptosis; Mitochondrion; Mitochondrion outer membrane
Manufacturer - Targets	This Bad antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-81 amino acids from the Central region of human Bad.
Bio Background	Bad is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB06939
Gene Name	BAD
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	18392
Antigen Source	HUMAN
Antigen Region	53-81
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 WB: 1:1000 WB: 1:1000 IHC-P: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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