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CASP10 Antibody (Center)

CASP10 Antibody (Center)

Item no.	ABC-AP1326c
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Cell Biology Cell Status Apoptosis Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Lan,Q., Morton,L.M. Blood 114 (2), 264-267 (2009) Kim,Y.R., Kim,K.M. Hum. Pathol. 40 (6), 868-871 (2009) Lisa-Santamaria,P. Biochim. Biophys. Acta 1793 (3), 561-571 (2009)
NCBI	NP_001193453.1,NP_001193471.1,NP_001221.2,NP_116756.2,NP_116758.1,NP_116759.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Caspase-10,CASP-10,Apoptotic protease Mch-4,FAS-associated death domain protein interleukin-1B-converting enzyme 2,FLICE2,ICE-like apoptotic protease 4,Caspase-10 subunit p23/17,Caspase-10 subunit p12,CASP10,MCH4
Similar products	Caspase-10, CASP10, FLICE2, MCH4, ICE-like apoptotic protease 4, Apoptotic protease Mch-4, CASP-10, FAS-associated death domain protein interleukin-1B-converting enzyme 2, Caspase-10 subunit p12, Caspase-10 subunit p23/17
Available
Manufacturer - Category	Primary Antibodies; Cancer; Cell Biology; Metabolism; RIG-l-like Receptor; Apoptosis; Apoptosis signaling
Manufacturer - Targets	This CASP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 164-192 amino acids from the Central region of human CASP10.
Bio Background	CASP1 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in the protein are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB18398
Gene Name	CASP10
Subtitle	Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	58951
Antigen Source	HUMAN
Antigen Region	164-192
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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