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CCDC99 Antibody (C-term)

CCDC99 Antibody (C-term)

Item no.	ABC-AP13504b
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	Arsenite-related gene 1 protein, hSpindly, Protein Spindly {ECO:0000255\|HAMAP-Rule:MF_03041}, Coiled-coil domain-containing protein 99 {ECO:0000255\|HAMAP-Rule:MF_03041}, Spindle apparatus coiled-coil domain-containing protein 1 {ECO:0000255\|HAMAP-Rule:MF_03041}, SPDL1 {ECO:0000255\|HAMAP-Rule:MF_03041}, Rhabdomyosarcoma antigen MU-RMS-404A
Available
Primary Accession	Q96EA4
Antigen Type	Synthetic Peptide
Application	IHC-P, WB
Bio Background	CCDC99 is required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment.
Bio References	Barisic, M., et al. Mol. Biol. Cell 21(12):1968-1981(2010) Gassmann, R., et al. Genes Dev. 24(9):957-971(2010) Chan, Y.W., et al. J. Cell Biol. 185(5):859-874(2009)
Clonality	Polyclonal
Clone/Animal Names	RB33449
Gene ID	54908
Gene Name	SPDL1 {ECO:0000255\|HAMAP-Rule:MF_03041}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	CCDC99 Antibody (C-term) (Cat. #AP13504b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the CCDC99 antibody detected the CCDC99 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	CCDC99 Antibody (C-term) (Cat. #AP13504b)immunohistochemistry analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CCDC99 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	Q4R7H3; NP_060255.3
Predicted	Pr
Isotype	Rabbit Ig
Calculated MW	70172
Antigen Region	459-488
Antigen Source	HUMAN
Target/Specificity	This CCDC99 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 459-488 amino acids from the C-terminal region of human CCDC99.
NCBI Accession	NP_060255.3

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 10/2/2025

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