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IMPDH1 Antibody (C-term)

IMPDH1 Antibody (C-term)

Item no.	ABC-AP13549b-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	Immunofluorescence, Western Blot, Immunohistochemistry
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Inosine-5'-monophosphate dehydrogenase 1 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMP dehydrogenase 1 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMPD 1 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMPDH 1 {ECO:0000255\|HAMAP-Rule:MF_03156}, 111205 {ECO:0000255\|HAMAP-Rule:MF_03156
Available
Primary Accession	P20839
Other Accession	D3ZLZ7; P50096; A0JNA3; NP_001136045.1; NP_001096075.1
Antigen Type	Synthetic Peptide
Bio Background	The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.
Bio References	Ohmann, E.L., et al. Pediatr Transplant 14(7):891-895(2010) Gensburger, O., et al. Pharmacogenet. Genomics 20(9):537-543(2010) Kagaya, H., et al. Basic Clin. Pharmacol. Toxicol. 107(2):631-636(2010) Ohmann, E.L., et al. J. Heart Lung Transplant. 29(5):509-516(2010) Shumei, L., et al. Adv. Exp. Med. Biol. 664, 293-297 (2010) :
Gene ID	3614
Gene Name	IMPDH1 {ECO:0000255\|HAMAP-Rule:MF_03156}
Reactivity	H
Predicted	B, M, Rat
Calculated MW	55406
Antigen Region	487-514
Antigen Source	HUMAN
Target/Specificity	This IMPDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-514 amino acids from the C-terminal region of human IMPDH1.
NCBI Accession	NP_000874.2; NP_001096075.1; NP_001136045.1; NP_001136046.1; NP_001136047.1; NP_001136048.1; NP_899066.1

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Amount: 80 ul

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