CASP6 Antibody (N-term)

Primary Antibodies; Cancer; Cell Biology; Metabolism; Neuroscience; Apoptosis

This gene encodes a protein which is a member of thecysteine-aspartic acid protease (caspase) family. Sequentialactivation of caspases plays a central role in the execution-phaseof cell apoptosis. Caspases exist as inactive proenzymes whichundergo proteolytic processing at conserved aspartic residues toproduce two subunits, large and small, that dimerize to form theactive enzyme. This protein is processed by caspases 7, 8 and 1, and is thought to function as a downstream enzyme in the caspaseactivation cascade. Alternative splicing of this gene results intwo transcript variants that encode different isoforms. [providedby RefSeq].

RB33636

Affinity Purified Rabbit Polyclonal Antibody (Pab)

33310

17-45

WB: 1:1000
WB: 1:1000
IHC-P: 1:10~50