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MIST Antibody (Center)

MIST Antibody (Center)

Item no.	ABC-AP13943c
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	CLNK, MIST, Cytokine-dependent hematopoietic cell linker, Mast cell immunoreceptor signal transducer
Available
Primary Accession	Q7Z7G1
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	MIST is a member of the SLP76 family of adaptors (see LCP2, MIM 601603; BLNK, MIM 604515). MIST plays a role in the regulation of immunoreceptor signaling, including PLC-gamma (PLCG1; MIM 172420)-mediated B cell antigen receptor (BCR) signaling and FC-epsilon R1 (see FCER1A, MIM 147140)-mediated mast cell degranulation (Cao et al., 1999 [PubMed 10562326]; Goitsuka et al., 2000, 2001 [PubMed 10744659] [PubMed 11463797]).
Bio References	Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Cronin, S., et al. Eur. J. Hum. Genet. 17(2):213-218(2009) Goitsuka, R., et al. J. Biol. Chem. 276(38):36043-36050(2001) Goitsuka, R., et al. Int. Immunol. 12(4):573-580(2000) Cao, M.Y., et al. J. Exp. Med. 190(10):1527-1534(1999)
Clonality	Polyclonal
Clone/Animal Names	RB21953
Gene ID	116449
Gene Name	CLNK
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	MIST Antibody (Center) (Cat. #AP13943c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the MIST antibody detected the MIST protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	NP_443196.2
Isotype	Rabbit Ig
Calculated MW	49554
Antigen Region	281-308
Antigen Source	HUMAN
Target/Specificity	This MIST antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-308 amino acids from the Central region of human MIST.
NCBI Accession	NP_443196.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 10/2/2025

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