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PIAS4 Antibody (N-term)

PIAS4 Antibody (N-term)

Item no.	ABC-AP14013a-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	PIAS4, PIASG, E3 SUMO-protein ligase PIAS4, PIASy, Protein inhibitor of activated STAT protein 4, Protein inhibitor of activated STAT protein gamma, PIAS-gamma, 632-
Available
Primary Accession	Q8N2W9
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	PIAS4 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway, the Wnt pathway and the steroid hormone signaling pathway. Involved in gene silencing. Promotes PARK7 sumoylation. In Wnt signaling, represses LEF1 and enhances TCF4 transcriptional activities through promoting their sumoylations.
Bio References	Kang, X., et al. Oncogene 29(41):5568-5578(2010) Liu, Y., et al. J. Invest. Dermatol. 130(5):1384-1390(2010) Zhang, C., et al. Cell. Immunol. 263(2):235-240(2010) Wang, J., et al. J. Biol. Chem. 283(34):23235-23243(2008) Imoto, S., et al. Biochem. Biophys. Res. Commun. 370(2):359-365(2008)
Clonality	Polyclonal
Clone/Animal Names	RB33956
Gene ID	51588
Gene Name	PIAS4
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	M
Legend image 1	PIAS4 Antibody (N-term) (Cat. #AP14013a) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the PIAS4 antibody detected the PIAS4 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	NP_056981.2
Isotype	Rabbit Ig
Calculated MW	56504
Antigen Region	44-73
Antigen Source	HUMAN
Target/Specificity	This PIAS4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-73 amino acids from the N-terminal region of human PIAS4.
NCBI Accession	NP_056981.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 9/4/2025

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