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OTU7B Antibody (C-term)

OTU7B Antibody (C-term)

Item no.	ABC-AP14281b-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB, IHC-P
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	OTUD7B, ZA20D1, OTU domain-containing protein 7B, Cellular zinc finger anti-NF-kappa-B protein, Zinc finger A20 domain-containing protein 1, Zinc finger protein Cezanne
Available
Primary Accession	Q6GQQ9
Antigen Type	Synthetic Peptide
Application	WB, IHC-P
Bio Background	OTU7B has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin. Negative regulator of nuclear factor NF-kappa-B.
Bio References	Bremm, A., et al. Nat. Struct. Mol. Biol. 17(8):939-947(2010) Jin, Z., et al. Cell 137(4):721-735(2009) Enesa, K., et al. J. Biol. Chem. 283(27):18582-18590(2008) Bohgaki, M., et al. Biochim. Biophys. Acta 1783(5):826-837(2008) Enesa, K., et al. J. Biol. Chem. 283(11):7036-7045(2008)
Clonality	Polyclonal
Clone/Animal Names	RB34874
Gene ID	56957
Gene Name	OTUD7B
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	OTU7B Antibody (C-term) (Cat. #AP14281b) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the OTU7B antibody detected the OTU7B protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Legend image 2	OTU7B Antibody (C-term) (AP14281b)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of OTU7B Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Type image 2	IHC-P
Dilution image 2	1:10~50
Other Accession	B2RUR8; NP_064590.2
Predicted	M
Isotype	Rabbit Ig
Calculated MW	92526
Antigen Region	757-784
Antigen Source	HUMAN
Target/Specificity	This OTU7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 757-784 amino acids from the C-terminal region of human OTU7B.
NCBI Accession	NP_064590.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 10/2/2025

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