Comparison

CHRM2 Antibody (Center)

Item no. ABC-AP14420c-ev
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications WB
Specific against Human (Homo sapiens)
Host Rabbit
Isotype IgG
Citations Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010):
Cannon, D.M., et al. Mol. Psychiatry (2010) In press:
Bosker, F.J., et al. Mol. Psychiatry (2010) In press :
NCBI NP_000730.1,NP_001006627.1,NP_001006628.1,NP_001006629.1,NP_001006630.1,NP_001006631.1,NP_001006632.1,NP_001006633.1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Muscarinic acetylcholine receptor M2,CHRM2
Similar products CHRM2, Muscarinic acetylcholine receptor M2
Available
Manufacturer - Category
Primary Antibodies; Antibody Collections; Neuroscience; GPCR Antibodies; Druggable G protein-coupled receptors (GPCRs)
Manufacturer - Targets
This CHRM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-364 amino acids from the Central region of human CHRM2.
Bio Background
The muscarinic cholinergic receptors belong to a largerfamily of G protein-coupled receptors. The functional diversity ofthese receptors is defined by the binding of acetylcholine to thesereceptors and includes cellular responses such as adenylate cyclaseinhibition, phosphoinositide degeneration, and potassium channelmediation. Muscarinic receptors influence many effects ofacetylcholine in the central and peripheral nervous system. Themuscarinic cholinergic receptor 2 is involved in mediation ofbradycardia and a decrease in cardiac contractility. Multiplealternatively spliced transcript variants have been described forthis gene.
Clonality
Polyclonal
Polyclonal Antibody Additonal Information
RB34390
Gene Name
CHRM2
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Predicted Reactivity
B, M, Pig, Rat
Calculated Molecular Weight
51715
Antigen Source
HUMAN
Antigen Region
336-364
Formulation
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution
WB: 1:1000
WB: 1:1000
Antigen Type
Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 80 ul
Available: In stock
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