Comparison

TNFSF14 Antibody (Center)

Item no. ABC-AP14595c
Manufacturer Abcepta
Amount 400 ul
Category
Type Antibody Primary
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications WB
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Similar products LIGHT, TNFSF14, soluble form, membrane form, HVEML, Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, CD258, HVEM-L, Herpesvirus entry mediator ligand
Available
Primary Accession
O43557
Antigen Type
Synthetic Peptide
Application
WB
Bio Background
The protein encoded by this gene is a member of the tumor
necrosis factor (TNF) ligand family. This protein is a ligand for
TNFRSF14, which is a member of the tumor necrosis factor receptor
superfamily, and which is also known as a herpesvirus entry
mediator (HVEM). This protein may function as a costimulatory
factor for the activation of lymphoid cells and as a deterrent to
infection by herpesvirus. This protein has been shown to stimulate
the proliferation of T cells, and trigger apoptosis of various
tumor cells. This protein is also reported to prevent tumor
necrosis factor alpha mediated apoptosis in primary hepatocyte. Two
alternatively spliced transcript variant encoding distinct isoforms
have been reported.
Bio References
Stiles, K.M., et al. J. Virol. 84(22):11646-11660(2010)
Jin, H.R., et al. Biochem. Biophys. Res. Commun. 400(4):581-586(2010)
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Cheung, T.C., et al. J. Immunol. 185(3):1949-1958(2010)
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Clonality
Polyclonal
Clone/Animal Names
RB34583
Gene ID
8740
Gene Name
TNFSF14
Subtitle
Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity
H
Legend image 1
TNFSF14 Antibody (Center) (Cat. #AP14595c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the TNFSF14 antibody detected the TNFSF14 protein (arrow).
Type image 1
WB
Dilution image 1
1:1000
Other Accession
NP_742011.2; NP_003798.2
Isotype
Rabbit Ig
Calculated MW
26350
Antigen Region
66-94
Antigen Source
HUMAN
Target/Specificity
This TNFSF14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the Central region of human TNFSF14.
NCBI Accession
NP_003798.2; NP_742011.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 400 ul
Available: In stock
available

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