Comparison

STC1 Antibody (C-term)

Item no. ABC-AP14863b-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Stanniocalcin-1, STC-1, STC1, STC
Available
Primary Accession
P52823
Other Accession
P97574; O55183; NP_003146.1
Antigen Type
Synthetic Peptide
Bio Background
This gene encodes a secreted, homodimeric glycoprotein
that is expressed in a wide variety of tissues and may have
autocrine or paracrine functions. The gene contains a 5' UTR rich
in CAG trinucleotide repeats. The encoded protein contains 11
conserved cysteine residues and is phosphorylated by protein kinase
C exclusively on its serine residues. The protein may play a role
in the regulation of renal and intestinal calcium and phosphate
transport, cell metabolism, or cellular calcium/phosphate
homeostasis. Overexpression of human stanniocalcin 1 in mice
produces high serum phosphate levels, dwarfism, and increased
metabolic rate. This gene has altered expression in hepatocellular,
ovarian, and breast cancers.
Bio References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Liu, G., et al. J. Natl. Cancer Inst. 102(11):812-827(2010)
Kottgen, A., et al. Nat. Genet. 42(5):376-384(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Trindade, D.M., et al. BMC Struct. Biol. 9, 57 (2009) :
Gene ID
6781
Gene Name
STC1
Reactivity
H
Predicted
M, Rat
Calculated MW
27621
Antigen Region
193-221
Antigen Source
HUMAN
Target/Specificity
This STC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-221 amino acids from the C-terminal region of human STC1.
NCBI Accession
NP_003146.1

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