ABCG2 (BCRP) Antibody (Center)

Primary Antibodies; Cancer; Metabolism; Signal Transduction

ABCG2 is a membrane-associated protein included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN2, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.

RB13782

Purified Rabbit Polyclonal Antibody (Pab)

72314

305-335

IF: 1:10~50
WB: 1:1000
IHC-P: 1:50~100
FC: 1:10~50