TLR2 Antibody (N-term)

Primary Antibodies; Cardiovascular; Immunology; Microbiology; Signal Transduction; Immunity; Inflammatory response; Innate immunity; Toll receptor signaling; Toll-Like Receptor; Toll-Like receptor signaling; Immune system process

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.

RB02403-02404

Purified Rabbit Polyclonal Antibody (Pab)

Pr

HUMAN

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Synthetic Peptide