CD86 Antibody (C-term)

Primary Antibodies; Immunology; Microbiology; Signal Transduction; Host cell receptor for virus entry; Viral entry into host cell; Host-virus interaction; Immunity; Toll-Like receptor signaling; Immune system process; T cell activation; Allograft rejection; Intestinal immune network for IgA production

This gene encodes a type I membrane protein that is amember of the immunoglobulin superfamily. This protein is expressedby antigen-presenting cells, and it is the ligand for two proteinsat the cell surface of T cells, CD28 antigen and cytotoxicT-lymphocyte-associated protein 4. Binding of this protein withCD28 antigen is a costimulatory signal for activation of theT-cell. Binding of this protein with cytotoxicT-lymphocyte-associated protein 4 negatively regulates T-cellactivation and diminishes the immune response. Alternative splicingresults in two transcript variants encoding different isoforms.Additional transcript variants have been described, but theirfull-length sequences have not been determined. [provided byRefSeq].

RB33620

Affinity Purified Rabbit Polyclonal Antibody (Pab)

37682

269-298

WB: 1:1000