Comparison

VPS11 Antibody (C-term)

Item no. ABC-AP16504b-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Vacuolar protein sorting-associated protein 11 homolog, hVPS11, RING finger protein 108, VPS11, RNF108
Available
Primary Accession
Q9H270
Other Accession
Q91W86; NP_068375.3
Antigen Type
Synthetic Peptide
Bio Background
Vesicle mediated protein sorting plays an important role
in segregation of intracellular molecules into distinct organelles.
Genetic studies in yeast have identified more than 40 vacuolar
protein sorting (VPS) genes involved in vesicle transport to
vacuoles. This gene encodes the human homolog of yeast class C
Vps11 protein. The mammalian class C Vps proteins are predominantly
associated with late endosomes/lysosomes, and like their yeast
counterparts, may mediate vesicle trafficking steps in the
endosome/lysosome pathway.
Bio References
Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Zhu, G.D., et al. Mol. Biol. Cell 20(4):1223-1240(2009)
Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)
Lehner, B., et al. Genome Res. 14(7):1315-1323(2004)
Gene ID
55823
Gene Name
VPS11
Reactivity
H
Predicted
M
Calculated MW
107837
Antigen Region
772-800
Antigen Source
HUMAN
Target/Specificity
This VPS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 772-800 amino acids from the C-terminal region of human VPS11.
NCBI Accession
NP_068375.3

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