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NKIRAS2 Antibody (Center)

NKIRAS2 Antibody (Center)

Item no.	ABC-AP16523c-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Cell Biology Cytoskeleton Western Blot Primary Antibodies small GTPases Ras Subfamily
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Tago, K., et al. J. Biol. Chem. 285(40):30622-30633(2010) Dieguez-Gonzalez, R., et al. Ann. Rheum. Dis. 68(4):579-583(2009) Fenwick, C., et al. Science 287(5454):869-873(2000)
NCBI	NP_001001349.1,NP_001138399.1,NP_001138400.1,NP_001138401.1,NP_060065.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	NF-kappa-B inhibitor-interacting Ras-like protein 2,I-kappa-B-interacting Ras-like protein 2,Kappa B-Ras protein 2,KappaB-Ras2,NKIRAS2,KBRAS2
Similar products	NKIRAS2, KBRAS2, NF-kappa-B inhibitor-interacting Ras-like protein 2, I-kappa-B-interacting Ras-like protein 2, Kappa B-Ras protein 2, KappaB-Ras2
Available
Manufacturer - Category	Primary Antibodies; Signal Transduction
Manufacturer - Targets	This NKIRAS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the Central region of human NKIRAS2.
Bio Background	Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP-and GDP-bound forms block phosphorylation of NFKBIB (By similarity).
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB36021
Gene Name	NKIRAS2
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	C, M, X
Calculated Molecular Weight	21508
Antigen Source	HUMAN
Antigen Region	36-64
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 1/1/2026

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