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DIAPH3 Antibody (C-term)

DIAPH3 Antibody (C-term)

Item no.	ABC-AP16587b-ev
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	DIAPH3, DIAP3, Protein diaphanous homolog 3, Diaphanous-related formin-3, MDia2, DRF3
Available
Primary Accession	Q9NSV4
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	DIAPH3 binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).
Bio References	DeWard, A.D., et al. J. Biol. Chem. 284(30):20061-20069(2009) Block, J., et al. J Microsc 231(3):506-517(2008) Beli, P., et al. Nat. Cell Biol. 10(7):849-857(2008) Yang, C., et al. PLoS Biol. 5 (11), E317 (2007) : Gupton, S.L., et al. J. Cell. Sci. 120 (PT 19), 3475-3487 (2007) :
Clonality	Polyclonal
Clone/Animal Names	RB35590
Gene ID	81624
Gene Name	DIAPH3
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	DIAPH3 Antibody (C-term) (Cat. #AP16587b) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the DIAPH3 antibody detected the DIAPH3 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	NP_001035982.1; NP_112194.2
Isotype	Rabbit Ig
Calculated MW	136926
Antigen Region	1061-1090
Antigen Source	HUMAN
Target/Specificity	This DIAPH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1061-1090 amino acids from the C-terminal region of human DIAPH3.
NCBI Accession	NP_001035982.1; NP_001245295.1; NP_001245296.1; NP_001245297.1; NP_001245298.1; NP_001245299.1; NP_112194.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 80 ul

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Delivery expected until 10/2/2025

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