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EPOR Antibody (Center)

EPOR Antibody (Center)

Item no.	ABC-AP16681c
Manufacturer	Abcepta
Amount	400 ul
Category	Oncology Antibodies By Cell Type Hematology Leukemia Lymphoma Flow Cytometry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	WB, FC, IF
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Lim, A.C., et al. Biochemistry 49(18):3797-3804(2010) Perrotta, S., et al. PLoS ONE 5 (8), E12015 (2010): Khankin, E.V., et al. PLoS ONE 5 (2), E9246 (2010): Wincewicz, A., et al. Folia Histochem. Cytobiol. 47(3):425-430(2009) Ketteler, R., et al. J. Biol. Chem. 278(4):2654-2660(2003)
NCBI	NP_000112.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Erythropoietin receptor,EPO-R,EPOR
Similar products	EPOR, Erythropoietin receptor, EPO-R
Available
Manufacturer - Category	Primary Antibodies; Cardiovascular; Immunology; Signal Transduction; Jak-STAT signaling KEGG
Manufacturer - Targets	This EPOR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-357 amino acids from the Central region of human EPOR.
Bio Background	This gene encodes the erythropoietin receptor which is amember of the cytokine receptor family. Upon erythropoietinbinding, this receptor activates Jak2 tyrosine kinase whichactivates different intracellular pathways including: Ras/MAPkinase, phosphatidylinositol 3-kinase and STAT transcriptionfactors. The stimulated erythropoietin receptor appears to have arole in erythroid cell survival. Defects in the erythropoietinreceptor may produce erythroleukemia and familial erythrocytosis.Dysregulation of this gene may affect the growth of certain tumors.Alternate splicing results in multiple transcript variants.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB30358
Gene Name	EPOR {ECO:0000303\|PubMed:2163695, ECO:0000312\|HGNC:HGNC:3416}
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Calculated Molecular Weight	55065
Antigen Source	HUMAN
Antigen Region	329-357
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	IF: 1:10~50 WB: 1:1000 FC: 1:10~50
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 3/5/2026

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