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RCAN1 Antibody (N-term)

RCAN1 Antibody (N-term)

Item no.	ABC-AP16791A-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Antibodies Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Applications	Immunofluorescence, Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Calcipressin-1, Adapt78, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, MCIP1, Regulator of calcineurin 1, RCAN1, ADAPT78, CSP1, DSC1, DSCR1
Available
Primary Accession	P53805
Other Accession	Q9JHG6; NP_004405.3; NP_981963.1
Antigen Type	Synthetic Peptide
Bio Background	The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.
Bio References	Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Tam, G.W., et al. Biochem. Soc. Trans. 38(2):445-451(2010) Lee, M.Y., et al. Hum. Mol. Genet. 19(3):468-479(2010) Sales, K.J., et al. Am. J. Pathol. 176(1):435-445(2010) Sales, K.J., et al. Biochim. Biophys. Acta 1793(12):1917-1928(2009)
Gene ID	1827
Gene Name	RCAN1
Reactivity	H
Predicted	M
Calculated MW	28079
Antigen Region	41-68
Antigen Source	HUMAN
Target/Specificity	This RCAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-68 amino acids from the N-terminal region of human RCAN1.
NCBI Accession	NP_004405.3; NP_981962.1; NP_981963.1

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Amount: 80 ul

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