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SOCS7 Antibody (C-term)

SOCS7 Antibody (C-term)

Manufacturer	Abcepta
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Specific against	other
Isotype	Ig
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Amount	400 ul
Host	Rabbit
Item no.	ABC-AP17111b
eClass 6.1	32160702
eClass 9.0	32160702
Available
Primary Accession	O14512
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity).
Bio References	Pazienza, V., et al. J. Gen. Virol. 91 (PT 7), 1678-1686 (2010) : Sasi, W., et al. BMC Cancer 10, 178 (2010) : Kremer, B.E., et al. Cell 130(5):837-850(2007) Zody, M.C., et al. Nature 440(7087):1045-1049(2006) Banks, A.S., et al. J. Clin. Invest. 115(9):2462-2471(2005)
Clonality	Polyclonal
Clone/Animal Names	RB37084
Gene ID	30837
Gene Name	SOCS7
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	SOCS7 Antibody (C-term) (Cat. #AP17111b) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SOCS7 antibody detected the SOCS7 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	Q8VHQ2; NP_055413.1
Predicted	M
Isotype	Rabbit Ig
Calculated MW	62969
Antigen Region	458-486
Antigen Source	HUMAN
Target/Specificity	This SOCS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-486 amino acids from the C-terminal region of human SOCS7.
NCBI Accession	NP_055413.1

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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ABC-AP17111b-datasheet.pdf

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Amount: 400 ul

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Delivery expected until 7/4/2024