Comparison

NPLOC4 Antibody (C-term)

Item no. ABC-AP17356b-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Nuclear protein localization protein 4 homolog, Protein NPL4, NPLOC4, KIAA1499, NPL4
Available
Primary Accession
Q8TAT6
Other Accession
Q9ES54; P60670; NP_060391.2
Antigen Type
Synthetic Peptide
Bio Background
The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope (By similarity).
Bio References
Liu, F., et al. PLoS Genet. 6, E1000934 (2010) :
Lass, A., et al. Exp. Cell Res. 314(14):2715-2723(2008)
McConnell, E., et al. Biochem. Biophys. Res. Commun. 355(4):1087-1090(2007)
Gevaert, K., et al. Nat. Biotechnol. 21(5):566-569(2003)
Botta, A., et al. Gene 275(1):39-46(2001)
Gene ID
55666
Gene Name
NPLOC4
Reactivity
H
Predicted
M, Rat
Calculated MW
68120
Antigen Region
456-484
Antigen Source
HUMAN
Target/Specificity
This NPLOC4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 456-484 amino acids from the C-terminal region of human NPLOC4.
NCBI Accession
NP_060391.2

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