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NKIRAS1 Antibody (Center)

NKIRAS1 Antibody (Center)

Item no.	ABC-AP17459c
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Cell Biology Cytoskeleton Western Blot Primary Antibodies small GTPases Ras Subfamily
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Isotype	IgG
Citations	Gerashchenko, G.V., et al. Exp. Oncol. 32(2):71-75(2010) Dieguez-Gonzalez, R., et al. Ann. Rheum. Dis. 68(4):579-583(2009) Barrios-Rodiles, M., et al. Science 307(5715):1621-1625(2005) Chen, Y., et al. Mol. Cell. Biol. 24(7):3048-3056(2004) Chen, Y., et al. J. Biol. Chem. 278(25):23101-23106(2003)
NCBI	NP_065078.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	NF-kappa-B inhibitor-interacting Ras-like protein 1,I-kappa-B-interacting Ras-like protein 1,Kappa B-Ras protein 1,KappaB-Ras1,NKIRAS1,KBRAS1
Similar products	NKIRAS1, KBRAS1, NF-kappa-B inhibitor-interacting Ras-like protein 1, I-kappa-B-interacting Ras-like protein 1, KappaB-Ras1, Kappa B-Ras protein 1
Available
Manufacturer - Category	Primary Antibodies; Signal Transduction
Manufacturer - Targets	This NKIRAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-76 amino acids from the Central region of human NKIRAS1.
Bio Background	Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP-and GDP-bound forms block phosphorylation of NFKBIB.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB37274
Gene Name	NKIRAS1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Predicted Reactivity	Pr
Calculated Molecular Weight	21643
Antigen Source	HUMAN
Antigen Region	48-76
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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