WDR4 Antibody (Center)

Q9EP82; A7E3S5; NP_061139.2

This gene encodes a member of the WD repeat protein
family. WD repeats are minimally conserved regions of approximately
40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),
which may facilitate formation of heterotrimeric or multiprotein
complexes. Members of this family are involved in a variety of
cellular processes, including cell cycle progression, signal
transduction, apoptosis, and gene regulation. This gene is excluded
as a candidate for a form of nonsyndromic deafness (DFNB10), but is
still a candidate for other disorders mapped to 21q22.3 as well as
for the development of Down syndrome phenotypes. Two transcript
variants encoding the same protein have been found for this gene.

10785

H

45490

HUMAN

NP_001247403.1; NP_001247404.1; NP_001247405.1; NP_001247406.1; NP_061139.2; NP_387510.1