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DUSP6 Antibody (N-term)

DUSP6 Antibody (N-term)

Item no.	ABC-AP17558A
Manufacturer	Abcepta
Amount	400 ul
Category	Neuroscience Neural Signaling Antibodies Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Chiappinelli, K.B., et al. Gynecol. Oncol. 119(1):146-150(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Nunes-Xavier, C.E., et al. J. Biol. Chem. 285(34):26417-26430(2010) Zhang, Z., et al. Carcinogenesis 31(4):577-586(2010) Wang, Z., et al. Mol. Vis. 16, 1696-1704 (2010) :
NCBI	NP_001937.2,NP_073143.2
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Dual specificity protein phosphatase 6,Dual specificity protein phosphatase PYST1,Mitogen-activated protein kinase phosphatase 3,MAP kinase phosphatase 3,MKP-3,DUSP6,MKP3,PYST1
Similar products	DUSP6, MKP3, PYST1, Dual specificity protein phosphatase 6, Dual specificity protein phosphatase PYST1, Mitogen-activated protein kinase phosphatase 3, MAP kinase phosphatase 3, MKP-3
Available
Manufacturer - Category	Primary Antibodies; Neuroscience
Manufacturer - Targets	This DUSP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-88 amino acids from the N-terminal region of human DUSP6.
Bio Background	The protein encoded by this gene is a member of the dualspecificity protein phosphatase subfamily. These phosphatasesinactivate their target kinases by dephosphorylating both thephosphoserine/threonine and phosphotyrosine residues. Theynegatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associatedwith cellular proliferation and differentiation. Different membersof the family of dual specificity phosphatases show distinctsubstrate specificities for various MAP kinases, different tissuedistribution and subcellular localization, and different modes ofinducibility of their expression by extracellular stimuli. Thisgene product inactivates ERK2, is expressed in a variety of tissueswith the highest levels in heart and pancreas, and unlike mostother members of this family, is localized in the cytoplasm. Twotranscript variants encoding different isoforms have been found forthis gene.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB36744
Gene Name	DUSP6
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H, M
Predicted Reactivity	B
Calculated Molecular Weight	42320
Antigen Source	HUMAN
Antigen Region	59-88
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000 WB: 1:1000 WB: 1:1000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 3/5/2026

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