FXYD7 Antibody (N-term)

Synthetic Peptide

This reference sequence was derived from multiple
replicate ESTs and validated by similar human genomic sequence.
This gene encodes a member of a family of small membrane proteins
that share a 35-amino acid signature sequence domain, beginning
with the sequence PFXYD and containing 7 invariant and 6 highly
conserved amino acids. The approved human gene nomenclature for the
family is FXYD-domain containing ion transport regulator.
Transmembrane topology has been established for two family members
(FXYD1 and FXYD2), with the N-terminus extracellular and the
C-terminus on the cytoplasmic side of the membrane. FXYD2, also
known as the gamma subunit of the Na, K-ATPase, regulates the
properties of that enzyme. FXYD1 (phospholemman), FXYD2 (gamma),
FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to
induce channel activity in experimental expression systems. This
gene product, FXYD7, is novel and has not been characterized as a
protein. [RefSeq curation by Kathleen J. Sweadner, Ph.D.,
sweadner@helix.mgh.harvard.edu.].

Polyclonal

53822

Affinity Purified Rabbit Polyclonal Antibody (Pab)

FXYD7 Antibody (N-term) (Cat. #AP18030a) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the FXYD7 antibody detected the FXYD7 protein (arrow).

1:1000

Rabbit Ig

1-30

This FXYD7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human FXYD7.