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PPP4R2 Antibody (Center)

PPP4R2 Antibody (Center)

Item no.	ABC-AP18485c-ev-80ul
Manufacturer	Abcepta
Amount	80 ul
Category	Oncology Antibodies Western Blot Primary Antibodies Skin Cancer
Type	Antibody Polyclonal
Applications	Western Blot
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Serine/threonine-protein phosphatase 4 regulatory subunit 2, PPP4R2
Available
Primary Accession	Q9NY27
Other Accession	NP_777567.1
Antigen Type	Synthetic Peptide
Bio Background	Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.
Bio References	Lee, D.H., et al. Nat. Struct. Mol. Biol. 17(3):365-372(2010) Chen, G.I., et al. J. Biol. Chem. 283(43):29273-29284(2008) Chowdhury, D., et al. Mol. Cell 31(1):33-46(2008) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : Gingras, A.C., et al. Mol. Cell Proteomics 4(11):1725-1740(2005)
Gene ID	151987
Gene Name	PPP4R2
Reactivity	H, M
Calculated MW	46898
Antigen Region	228-254
Antigen Source	HUMAN
Target/Specificity	This PPP4R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 228-254 amino acids from the Central region of human PPP4R2.
NCBI Accession	NP_777567.1

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Amount: 80 ul

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