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mouse CASP3 Antibody (N-term S12)

mouse CASP3 Antibody (N-term S12)

Item no.	ABC-AP18708a
Manufacturer	Abcepta
Amount	400 ul
Category	Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Antibodies Cell Biology Cell Status Apoptosis Western Blot Primary Antibodies
Type	Antibody Polyclonal
Applications	WB
Specific against	Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Citations	Srikanth, C.V., et al. Science 330(6002):390-393(2010) Li, F., et al. Cell Stem Cell 7(4):508-520(2010) Wang, L., et al. J. Neurosci. 30(39):13201-13210(2010) Gascon, E., et al. J. Neurosci. 30(37):12414-12423(2010) Bohsali, A., et al. BMC Microbiol. 10, 237 (2010) :
NCBI	NP_033940.1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Caspase-3,CASP-3,Apopain,Cysteine protease CPP32,CPP-32,LICE,Protein Yama,SREBP cleavage activity 1,SCA-1,Caspase-3 subunit p17,Caspase-3 subunit p12,Casp3,Cpp32
Similar products	Caspase-3, Apopain, Cysteine protease CPP32, Protein Yama, SREBP cleavage activity 1, Caspase-3 subunit p17, Caspase-3 subunit p12, Casp3, Cpp32, LICE, CASP-3, CPP-32, SCA-1
Available
Manufacturer - Category	Primary Antibodies; Antibody Collections; Cancer; Cell Biology; Neuroscience; Amyotrophic Lateral Sclerosis (ALS)
Manufacturer - Targets	This mouse CASP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of mouse CASP3.
Bio Background	CASP3 is involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-\|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9 (By similarity). Cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes.
Clonality	Polyclonal
Polyclonal Antibody Additonal Information	RB39712
Gene Name	Casp3
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	M
Calculated Molecular Weight	31475
Antigen Source	MOUSE
Antigen Region	1-30
Formulation	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Dilution	WB: 1:1000
Antigen Type	Synthetic Peptide

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 1/1/2026

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