Comparison

CRADD Antibody (Center)

Item no. ABC-AP18802C-ev-80ul
Manufacturer Abcepta
Amount 80 ul
Category
Type Antibody Polyclonal
Applications Western Blot
Specific against other
Host Rabbit
Isotype Ig
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Death domain-containing protein CRADD, Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD, RAIDD
Available
Primary Accession
P78560
Other Accession
NP_003796.1
Antigen Type
Synthetic Peptide
Bio Background
The protein encoded by this gene is a death domain
(CARD/DD)-containing protein and has been shown to induce cell
apoptosis. Through its CARD domain, this protein interacts with,
and thus recruits, caspase 2/ICH1 to the cell death signal
transduction complex that includes tumor necrosis factor receptor 1
(TNFR1A), RIPK1/RIP kinase, and numbers of other CARD
domain-containing proteins.
Bio References
Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
Jang, T.H., et al. Biochim. Biophys. Acta 1804(7):1557-1563(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :
Heikaus, S., et al. Cell. Oncol. 32 (1-2), 29-42 (2010) :
Gene ID
8738
Gene Name
CRADD
Reactivity
H
Calculated MW
22745
Antigen Region
69-98
Antigen Source
HUMAN
Target/Specificity
This CRADD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the Central region of human CRADD.
NCBI Accession
NP_003796.1

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