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PRICKLE1 Antibody (C-term)

PRICKLE1 Antibody (C-term)

Item no.	ABC-AP18864B
Manufacturer	Abcepta
Amount	400 ul
Category	Antibodies Primary Antibodies
Type	Antibody Primary
Format	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Applications	WB
Specific against	other
Host	Rabbit
Isotype	Ig
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Similar products	RILP, PRICKLE1, Prickle-like protein 1, REST/NRSF-interacting LIM domain protein 1
Available
Primary Accession	Q96MT3
Antigen Type	Synthetic Peptide
Application	WB
Bio Background	This gene encodes a nuclear receptor that may be a negative regulator of the Wnt/beta-catenin signaling pathway. The encoded protein localizes to the nuclear membrane and has been implicated in the nuclear trafficking of the transcription repressors REST/NRSF and REST4. Mutations in this gene have been linked to progressive myoclonus epilepsy. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 3.
Bio References	Smith, N.L., et al. Circ Cardiovasc Genet 3(3):256-266(2010) Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) : Perry, J.R., et al. Diabetes 58(6):1463-1467(2009) Narimatsu, M., et al. Cell 137(2):295-307(2009) Shimojo, M. J. Biol. Chem. 283(50):34880-34886(2008)
Clonality	Polyclonal
Clone/Animal Names	RB39636
Gene ID	144165
Gene Name	PRICKLE1
Subtitle	Affinity Purified Rabbit Polyclonal Antibody (Pab)
Reactivity	H
Legend image 1	PRICKLE1 Antibody (C-term)(Cat. #AP18864b) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the PRICKLE1 antibody detected the PRICKLE1 protein (arrow).
Type image 1	WB
Dilution image 1	1:1000
Other Accession	NP_001138353.1
Isotype	Rabbit Ig
Calculated MW	94300
Antigen Region	678-704
Antigen Source	HUMAN
Target/Specificity	This PRICKLE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 678-704 amino acids from the C-terminal region of human PRICKLE1.
NCBI Accession	NP_001138353.1; NP_001138354.1; NP_001138355.1; NP_694571.2

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 9/4/2025

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